EASY OPIATE DETOXIFICATION FROM BUPRENORPHINE (SUBUTEX, SUBOXONE)
Buprenorphin (subutex)-detox of opiate dependent patients is a form of rapid detox which has been applied in the U.S. and some European countries since the nineties. Normally, the treatment lasts from 5 to 7 days providing a comfortable and painless transition to a clean state of body. A gradual detoxification process doesn’t allow any physical or psychological stress for the patient. This is crucial for opiate dependent patients.
Buprenorphin is a semi-synthetic opioid receptors agonist/antagonist. It doesn’t cause euphoria, a drug dosage tolerance increase, nor risks of overdose like methadone. It allows quitting opiates without any pain. Within a few days a person becomes free of drugs. After performing drugs test it’s possible to use an implant against relapse.
The agonist effects of buprenorphine increase linearly with increasing doses of the drug until at moderate doses they reach a plateau and no longer continue to increase with further increases in dose-the "ceiling effect." Thus, buprenorphine carries a lower risk of abuse, addiction, and side effects compared to full opioid agonists. In fact, in high doses and under certain circumstances, buprenorphine can actually block the effects of full opioid agonists and can precipitate withdrawal symptoms if administered to an opioid-addicted individual while a full agonist is in the bloodstream.
Suboxone is a combination of Buprenorphine and Naloxone. Suboxone is sublingual, which means it is taken under the tongue. Suboxone cannot be injected, because the Naloxone element will cause instant opiate withdrawal.
In October 2002, the FDA approved the buprenorphine monotherapy product, Subutex for use in opioid addiction treatment.
Although medically assisted detox options are available, the preferred method is Ambulatory Detoxification.